In his 1917 review of the history of asthma, Dr. Orville Henry Brown said the following of Merkel:
Merkel, after an exhaustive survey of the literature of asthma, comes to the following conclusions:
That's all I have for today.
- Asthma is an affection of the bronchi caused by a neurosis or by an over-stimulation of the nerves of the respiratory system.
- The cramps are sometimes useful for the purpose of preventing the entrance of foreign bodies into the respiratory tract.
- But from various causes this function may be exercised when it is of no benefit or use.
- The spasm involves the muscles of respiration.
- Bronchorrhea, bronchitis, dilation of the bronchi,and congestion commonly result.
- Asthma is usually complicated by catarrh, emphysema, and heart disease.
- Treatment is most efficacious if directed toward the nervous system.
- Inhalations are the most efficacious treatment.
- The location of the neurosis cannot be stated but on that account cannot be denied. (1, page 35)
- Brown, Orville Harry, "Asthma, presenting an exposition of nonpassive expiration theory," 1917, St. Louis, C.V. Mosby Company; reference used: "Merkel, L.: Schmidt's Jahrb., 1861, cix, p. 225.
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